Not compatible

Does 16GB DDR5 (1x16GB) work with the A520?

No — not compatible: 16GB DDR5 (1x16GB) with A520. Memory mismatch: DDR5 RAM in a DDR4-only board. Live eBay prices.

How they line up

Spec
A520 A520
16GB DDR5 (1x16GB) 16GB DDR5 (1x16GB)
Socket
AM4
Memory
DDR4
DDR5

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16GB DDR5 (1x16GB)
A520

Common questions

Memory mismatch: DDR5 RAM in a DDR4-only board.