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Not compatible

Does 16GB DDR5 SO-DIMM work with the B550?

No — not compatible: 16GB DDR5 SO-DIMM with B550. Memory mismatch: DDR5 RAM in a DDR4-only board. Live eBay prices.

How they line up

Spec
B550 B550
16GB DDR5 SO-DIMM 16GB DDR5 SO-DIMM
Socket
AM4
—
Memory
DDR4
DDR5
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16GB DDR5 SO-DIMM
B550

Common questions

Memory mismatch: DDR5 RAM in a DDR4-only board.